> If there is something out there that is better by a wide enough margin to justify giving up that established ecosystem, I'd love to hear about it. The ecosystem has plenty of imperfections, but I haven't come across anything yet that seems nearly comprehensive enough to displace the incumbent here.

David Mark's My Library[0] is the best DOM library available by a wide margin. It has supreme browser support, and it's "modular" with a custom builder. The code is so solid that many people have borrowed from it, including the jQuery project and myself.

I've also created a DOM library, but with a more limited feature set (it's only a few months old). See my submissions for details.

[0]: http://www.cinsoft.net/mylib.html