Re:In SSRI withdrawal, brain zaps go from overlooked symptom...
by math_dandy on Friday October 11, 2024 @04:25PM
(#41813376)
I echo your experience. Effexor/Venlafaxine are absolute poison. I tapered off of it slowly over the last two months under doctor’s supervision. The day after I took my last dose — small thanks to the tapering — I’ve had constant brain zaps, wobbly vision, horrible perpetual nausea, cold sweats, and inability to sleep more than an hour at a time. It’s been two weeks so far of lying in a dark quiet room waiting for things to resolve so I can go back to my wife/kids/job/life. Still no noticeable improvement. On sick leave for the first time in my life.
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Re:In SSRI withdrawal, brain zaps go from overlooked symptom...
by zahllos on Friday October 11, 2024 @05:43PM
(#41814063)
I can also confirm brain zaps both when I tapered down and if I missed a dose. It was unpleasant but I put up with it when reducing my dose. I changed from it because it caused insomnia as a side effect badly enough that it was worse than the problem.
My understanding (which may be incorrect, not a doctor) is that you need a higher dose to achieve the N part of the SNRI. I wonder if this somehow linked to the experience. On lower doses of SSRIs I never had any such experiences.
Re:In SSRI withdrawal, brain zaps go from overlooked symptom...
by nixonpjoshua on Friday October 11, 2024 @05:55PM
(#41814205)
I would guess it has more to do with the serotonin, Atomoxetine has small S activity and large N activity and relatively it can be discontinued much easier than any of these other drugs.
Re:In SSRI withdrawal, brain zaps go from overlooked symptom...
by zahllos on Saturday October 12, 2024 @03:41PM
(#41821831)
That's what I thought as well. On the medication I was on afterwards it only inhibited serotonin reuptake and the dose was lower. I imagine a really high dose would do the same thing as well.