It's the same effect as adding async code to Python or Rust, suddenly the entire team and the entire codebase (and often dependency choices) must adhere to it.
You can choose to make a single flow in your application an effect program. Or you can base most of your functions around it. It's really up to you how and where it's used. If you want to use an effect within non-effect code, that's easy to do, too.
You can think of effects like values. The value is obtained by executing the effect. Until it's called, the effect can be placed anywhere, in any function, in a generator, within promises, etc. Once you need its value, you execute it. It's compatible with most code bases as long as you can execute it to get the value. It's really up to the developer how portable they want their effects to be.
Passing Effects around will similarly infect the entire codebase, resulting in the entire dev team who interacts with it needing to buy in. Limiting the output of Effects to a single module owned by one zealot dev undermines having it around in the first place and it'll get removed and replaced as soon as that person leaves or gives up the fight.