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Re:On 17th Century "Cocaine" by DisgracePlacard on Thursday October 10, 2024 @01:02AM (#41795690)
I'm no chemist, but according to wikipedia, cuscohygrine is found in belladona plants and it metabolizes into hygrine. So that could be what he's referring to?
Re:On 17th Century "Cocaine" by stef25 on Thursday October 10, 2024 @01:31PM (#41801164)
I read the same wikipedia page and that statement is confusing if not incorrect. Hygrine is a not a metabolite of cuscohygrine, it's in fact the other way round: hygrine is the precursor and cuscohygrine is the metabolite.

The first reference on that page is "The role of hygrine in the biosynthesis of cuscohygrine and hyoscyamine"