Re:Chemistry Nobel: Computational protein design and protein...
by flobosg on Wednesday October 09, 2024 @02:25PM
(#41791069)
> Rosetta used sequence homology
Rosetta used remote sequence homology to generate the MSAs and find template fragments, which at the time was innovative. A similar strategy is employed for AlphaFold’s MSAs containing the evolutionary couplings.
Rosetta used remote sequence homology to generate the MSAs and find template fragments, which at the time was innovative. A similar strategy is employed for AlphaFold’s MSAs containing the evolutionary couplings.