You know how the OceanGate sub imploded so fast that their brains didn't even have time to register they were dead?

If the basic laws of the universe change, we'll be disincorporated before we have a chance to know it's happening, because it will happen at whatever the speed of light is in the new balance, and the chemical processes that make us tick will change to other chemical processes that don't actually work anymore.

In the new universe silicon based life might function. Or stars might not work anymore.