NixOS sits between Debian and Gentoo, as it maintains an output that's capable of existing independently of the rest of the system (like Debian) but is designed to use the current host as a builder (like Gentoo). Gentoo doesn't have any way to keep individual builds separate from the system as a whole, as intimated in the article, so you need to work out how to keep the two worlds separate while you do the build.

I think what they're suggesting winds up being pretty similar to what you suggest, just with the right plumbing to make it work in a Gentoo system. NixOS would need different plumbing, I'm not sure whether they've done it yet or how but I can easily imagine it being more straightforward than what Gentoo is needing to do.