As far as I know jQuery is written with "native API", so there is obviously a way to do this in JavaScript.

    document.body.addEventListener("click", function(e) { 
      if (e.target.className == "clicky") {
        doSomething();
      }
    }, false);

document.getElementsByClassName('clicky').forEach(function(el) { el.addEventListener('click', doSomething); });

I'm not sure that works. getElementsByClassName (and Id and querySelector) returns a NodeList, not an Array, so there's no foreach, you have to convert it to an array first.

Array.prototype.slice.call(document.getElementsBy....

That's also a ton of tying and a lot of code that a minifier can't reduce. I guess its possible, but do you really want to writing such verbose code?