I’m not sure when infinite descent would be considered to have been formally proven to a modern mathematician but I bet it wasn’t in Euclid’s time!
So if you manage to produce an infinite sequence of strictly decreasing positive integers starting at a particular positive integer, then you've reached a contradiction.
In practice though, concepts with infinity are very tricky, and the Greeks definitely did not have a strong accurate theory of infinity, Aleph-zero even, much less (as is the point talking about the sqrt(2)), the reals.
In this case, I think embedded in a high school proof would be the assumption that for any integer you can list there are not an infinite number smaller than them. This is manifestly true about the integers, but it is not true for the rationals, despite the two sets having the same cardinality, and a solid proof would need to be able to distinguish the reasons why. It’s this part that I think would be beyond the Greeks.
> Rational numbers or fractions must have a simplest form.
They make no claim about uniqueness, but that is not needed in the argument.
Then if we figure out that both p and q are even, it means that p/q can be simplified (by dividing p and q by 2), which contradicts the assumption about the simplest form - and we don't need to use the infinite descent.