What to Know About California's Covid Surge

Re:What to Know About California's Covid Surge by pjkundert on Sunday July 21, 2024 @09:56PM (#41030195)

Neither of the referenced studies note when the treatment started; one states "plus standard NHS treatment", which implies presentation at a hostpital -- usually days after onset of symptoms.

Virtually all of the studies that do indicate treatment initiation within 1-3 days of onset of symptoms do strongly indicate effectiveness.

It seems ... odd to avoid disclosing average start of treatment from onset of symptoms, don't you think? Especially when this appears to be the primary determinant of successful treatment in numerous (>100) studies?

See: https://c19ivm.org/meta.html

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Re:What to Know About California's Covid Surge by pjkundert on Sunday July 21, 2024 @10:11PM (#41030292)

Here's a graph of onset of treatment vs. therapeutic effectiveness: https://c19ivm.org/mr/mr-all-delay.svg

Literally linearly from 100% efficacy to 0% efficacy over 7 days from onset of symptoms. Linear, over ~100 studies!

You don't see that kind of statistically profound predictive accuracy often; but when you do, you sit up and take notice.

Furthermore, in various other anti-viral treatments that are considered effective, onset-of-treatment is a critical determinant. Typically, over 24 to 48 hours after onset, treatment is pointless.

Why not consider that important to address (or even mention?) in Ivermectin studies? The mind boggles...

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