The only one I've listened to was him interviewing Donald Knuth which was worth listening to, tho from time to time I got the impression of an interviewer that didn't quite know enough to do the interview.

If you like podcasts of a very intelligent person interviewing very accomplished guest thinkers, Sean Carroll's Mindcast is slightly higher level: https://www.preposterousuniverse.com/podcast/ (tho I don't think Donald Knuth has been on that one, lots of other computer folks have).