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A comment on Gilead Shot Prevents All HIV Cases in Trial of African Women. Parent comment
https://www.nejm.org/doi/full/10.1056/NEJMoa2034577#t2
Yes, the primary endpoint shown in here was comparing 7 days after dose 2 of the vaccine to 7 days after dose 2 of the placebo group. (table 2):
https://www.nejm.org/cms/10.1056/NEJMoa2034577/asset/619bcb1...
However, figure 3 breaks down the efficacy vs. time, and it shows no effect like he describes:
https://www.nejm.org/cms/10.1056/NEJMoa2034577/asset/fe40d07...
Instead, the vaccine and control groups were about the same until roughly day 10-12 after the first dose, and then dramatically diverged (though not as decisively as after dose 2).
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https://www.nejm.org/doi/full/10.1056/NEJMoa2034577#t2
Yes, the primary endpoint shown in here was comparing 7 days after dose 2 of the vaccine to 7 days after dose 2 of the placebo group. (table 2):
https://www.nejm.org/cms/10.1056/NEJMoa2034577/asset/619bcb1...
However, figure 3 breaks down the efficacy vs. time, and it shows no effect like he describes:
https://www.nejm.org/cms/10.1056/NEJMoa2034577/asset/fe40d07...
Instead, the vaccine and control groups were about the same until roughly day 10-12 after the first dose, and then dramatically diverged (though not as decisively as after dose 2).