Researchers identify major driver of inflammatory bowel and related diseases

Re:Researchers identify major driver of inflammatory bowel a... by blastadon on Wednesday June 05, 2024 @10:25PM (#40592791)

I was diagnosed with colitis in my early 20s. Since I was 13, I had been using an acne medication containing benzoyl peroxide daily. Once I stopped using this medication, my symptoms drastically improved. While I can't prove it, I believe the acne medicine may have triggered my colitis.

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Re:Researchers identify major driver of inflammatory bowel a... by kunai on Wednesday June 05, 2024 @10:40PM (#40592860)

Doesn't seem like that far of a stretch given that Accutane (another acne medication) has been linked to IBD as well. There are a lot of drugs that interfere with the gut microbiota, of which its dysbiosis is often linked to the development of IBD. We're still in the infancy of understanding the pharmacokinetics of drugs as far as they relate to the gut and the ability of drugs to modulate the microbiome.

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Re:Researchers identify major driver of inflammatory bowel a... by jnwatson on Thursday June 06, 2024 @12:58AM (#40593665)

Isotretinoin and benzoyl peroxide are not remotely similar drugs. They have completely different mechanisms of action. That they both treat acne is essentially a coincidence.

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