The e-reader UI is generally so much better than paper, if a book is not available for kindle, I'll usually find something else to read. Pale Fire is a special case book where you want two have bookmarks where you are currently working. I read Chuck Palahniuk's Diary on paper, and an e-reader would definitely have ruined it.
Technical books with a lot of charts, diagrams, monospaced code examples, etc can highlight the weaknesses of e-readers. PDFs are almost always better on a tablet.
But for like, words-in-a-row novels that don't mind being re-wrapped, there is no comparison, for me. e-Reader every time.
Which is 98% of novels. e-Readers are even great for books with lots of end notes or foot notes. It's great for flipping between those. I had no problem reading Infinite Jest, for example.
I guess if my copy of Pale Fire had hyperlinked all the poem line mentions, I would have been fine. :)
Now I'm wondering if I could write a quick script to annotate mine thusly...
I'm the kind of reader that goes back and forth when reading a novel. I like to go back and re-read when a character was introduced, or simply go back a few pages.
The UI of the Kindle sucks for this. It excels at finding a specific sentence, of course, but not for the kind of flipping pages I enjoy doing.
* Control of text size * Weight
I forget what it was, but at some point I was excitedly reading a new hardback -- and found it so heavy to read in bed that I bought the Kindle edition in addition to the paper one. This also applies for travel, doubly so.
They do take up a shitload less space, which is a pretty big advantage, though.