There's a profiler cell magic for Notebooks which helps identify if you run out of VRAM (it says what runs on CPU and GPU). There's an open PR to turn on low-VRAM reporting as a diagnostic. CuDF is impressive, but getting a working setup can be a PITA (and then if you upgrade libraries...). Personality I think it fits in the production pipeline for obvious bottlenecks on well tended configurations, using it in the r&d flow might cost diagnostic time getting and keeping it working (YMMV etc)