Re:Toxoplasma Gondii significantly alters wolf behavior
by jimmygrapes on Wednesday May 29, 2024 @10:21PM
(#40519490)
You're also immunocompromised if you slept poorly or are dehydrated or malnourished (as many are, even if they don't know it). I agree that it's a poor blanket term.
Re:Toxoplasma Gondii significantly alters wolf behavior
by chasil on Wednesday May 29, 2024 @11:38PM
(#40519841)
The question is how your medication interacts with "somatic hypermutation" which enables your dendritic cells to launch the cascade via t-cells which triggers antibody production by your b-cells.
It would be useful to understand how your medication interacts with this process.
https://m.youtube.com/watch?v=lXfEK8G8CUI
Somatic hypermutation has a small discussion in the Kerzegast book.
I understand that somatic hypermutation, by the removal of uracil, plays two roles, first in initial recognition of a pathogen, then second in tuning the response for variants.
As I understand it, this only happens in germinal centers, the lymph nodes.
https://www.scribd.com/document/664375598/IMMUNE-by-Philipp-...
This is a question for an infectious disease specialist.
I use immunosuppressive medication to manage a chronic condition, so I assume my immune function is worse than someone not using such, but better than e.g. someone undergoing chemotherapy.
Does this make me immunocompromised or not? Or, where does it place me on the scale? What precautions should I take?