I think it is fine & better for society to have applications and models for things we don't fully understand... We can model lots of small aspects of weather, and we have a lot of factors nailed down, but not necessarily all the interactions.. and not all of the factors. (Additional example for the same reason: Gravity)

Used responsibly. Of course. I wouldn't think an AI model designing an airplane that no engineers understand how it works is a good idea :-)

And presumably all of this is followed by people trying to understand the results (expanding potential research areas)