Cardio toxicity cannot be ignored, especially in the typical context of consuming cocaine- dehydration, high amount of physical activity and sleep deprivation.

Any stimulant is potentially harmful, especially one as powerful as this. Even ephedrine, which is considered relatively mild, is actually dangerous.

And that's if you don't consider risks that are inherent to the drug's price- cocaine is expensive and thus frequently isn't too pure, to say the least. Pretty obvious how it affects its side-effect profile