If the well the global minimum lives in is sufficiently small—if it is a sufficiently local event—then your stochastic search is bound to fail. At the limit, you have a discontinuity, a global minimum which literally has no global presence and is essentially impossible to find (you can show expected convergence times going to infinity as the minimum looks more and more discontinuous).
Fortunately, few processes are genuinely discontinuous and they usually have some kind of non-local "well of attraction". But in higher and higher dimensions, these wells can be made to appear nearly infinitely narrow.
All together this enforces the principle of the curse of dimensionality. High dimensionality hurts you in statistics and search unless every dimension is just chock full of signal.
Check out Bill Thurston's comment on why this is deeply misleading geometrically:
http://mathoverflow.net/questions/53119/volumes-of-n-balls-w...
As several commenters there point out, if you must choose a ratio, a more geometrically natural choice would be the ratio of the unit sphere to its circumscribed cube (which decreases monotonically) or to its inscribed cube (which increases monotonically).
I agree with the comments on MathOverflow though.
There's some inherent flaw here - as 'pegging' the size of unit cube to its 1-dimensional parameter, the length, does not make the volume to vanish.
Unit cubes are constrained such that all of their measurements are unit length---something which ensures that their volume is constantly 1. They do this by getting spiky, as xyzzyx mentioned. The distance to cross them shrinks as the vertex distance grows.
So they start to look totally different in high dimensions, evidenced by the ball's vanishing measure.
> And so pegging the size of our unit ball to its 1-dimensional parameter, the radius, causes its volume to vanish.
Funny. I was just going to enter a comment how that was the most useful intuition in the whole thread.
The spheres are a strictly increasing sequence of sets, but the measures we call "volume" are growing even faster.
Again, however, the radius isn't changing. I don't think of unit balls as being spiky--they're still rotationally invariant in all d rotational degrees of freedom, so calling them spiky doesn't sit well with me.
Instead, imagine you lived on a line, only walking up and back along it forever. Then, one day, someone introduced you to the plane and then a volume. These are vastly larger than the space you were afforded by the line: exponential blowup.
It's also driven home by how the Lesbegue measure in d-dimensions assigns zero measure to all (d-1)-dimensional (or lesser) objects. Adding a dimension just makes space immensely larger.
And so pegging the size of our unit ball to its 1-dimensional parameter, the radius, causes its volume to vanish.
[1] Wolfram Alpha chart showing the volume of the n-sphere in units of pi http://www.wolframalpha.com/input/?i=pi%5E%28n%2F2-1%29%2FGa...