First-in-human implantation of bionic device to halt Crohn's disease

Re:First-in-human implantation of bionic device to halt Croh... by jml78 on Monday April 01, 2024 @10:13AM (#39894377)

My wife is on a biologic for psoriatic arthritis. We are scared of the long term impacts around cancer. Within 8 years of being on various biologics she was diagnosed with cancer late last year in her early 40s. No family history of cancer.

We have no evidence biologics caused it but the fact that they reduce t-cell activity, it is definitely plausible. That is why all of them disclose the blanket cancer risks. She is not currently cancer free but we are concerned that the next one will be something with a much worse 5 year outlook

We would rather her not be on them but they are the best thing that currently exists.

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Re:First-in-human implantation of bionic device to halt Croh... by computer7050 on Monday April 01, 2024 @11:03AM (#39894868)

Rinvoq?

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Re:First-in-human implantation of bionic device to halt Croh... by jml78 on Monday April 01, 2024 @11:20AM (#39895070)

That is one she has been on in the past. She has gone thru about 8 trying to find one that works best for her.

She is currently on tremfya

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Re:First-in-human implantation of bionic device to halt Croh... by computer7050 on Monday April 01, 2024 @12:25PM (#39895889)

Thanks for the response. I have a family member about to start on Rinvoq and cancer risk is weighing on my mind as well.

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Re:First-in-human implantation of bionic device to halt Croh... by jml78 on Monday April 01, 2024 @01:08PM (#39896384)

I am probably sensitive because my mom passed away due to stroke prior to my wife being on Rinvoq but that was a bigger concern for me when my wife went on it. Learn to identify stroke symptoms.

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Re:First-in-human implantation of bionic device to halt Croh... by TheLML on Saturday April 06, 2024 @05:29PM (#39955753)

I've been on Rinvoq since last summer and I delayed getting on it for that very reason. Reading the risks was really not making me feel well, after I've already taken multiple other medications. The worst part is, that it doesn't work as perfectly as some previous meds have. But at least I can enjoy eating out occasionally again without much worry and can travel again. That quality of life improvement puts it into a slightly better perspective again.

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