tl;dr - Machine intelligences existed in Dune history, were discovered to be secretly controlling humanity (through abortion under false pretenses, forced sterilization, emotional/social control, and other ways), then were purged and replaced with a religious commandment: "Thou shalt not make a machine in the likeness of a human mind"
tl;dr - Machine intelligences existed in Dune history, were discovered to be secretly controlling humanity (through abortion under false pretenses, forced sterilization, emotional/social control, and other ways), then were purged and replaced with a religious commandment: "Thou shalt not make a machine in the likeness of a human mind"