Only sort-of. One of my favorite series has a situation where a terrorist is trying to destroy a wormhole - the only practical route for one particular planet to the rest of the galaxy. While the analogy is imperfect, it's basically permanently filling the only narrow channel that a ship can get through to the outside world. It's burning the bridge to the outside world. The Wormhole part of it is immaterial.

Consider that a lot of the best Star Trek stories are merely allegory for our own struggles. Some of them are pretty thinly veiled (The half-black-half-white people hate the half-white-half-black people) but even a kid can pierce that veil and understand and say "Oh... racism is stupid"

I think the "____ in space" effect is probably more related to poor writing then a specific component of the genre.