I thought that was a shot at climate change and natural evolution of the organism adapting to be tolerant of warmer temperatures.

It wasn't a documentary.

Fungi don't really need any help. Only reason they aren't even worse than what was depicted in TLoU is there's really no reason for them to be. There is literally no place on earth where you can stand and not be literally covered in all the fungal spores floating about. They are already ubiquitous. Human mind control would only reduce their fitness.

Yep, this is how you can make your own sourdough starter just by mixing some water and flour and leaving it out! Natural yeast spores all around us.