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A comment on Root cause of Alzheimer's may be fat buildup in brain cells, research suggests. Parent comment

Re:Root cause of Alzheimer's may be fat buildup in brain cel... by crakenzak on Wednesday March 20, 2024 @04:14AM (#39763889)
The insulin protein promotes glucose (not fats) uptake into the muscles (~75%), liver (~15%), and other tissue (~10%) to aggressively lower blood sugar levels back to a total circulating amount of ~5g.
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Re:Root cause of Alzheimer's may be fat buildup in brain cel... by spudlyo on Wednesday March 20, 2024 @10:34AM (#39767189)
In the obese, glucose is preferentially directed to adipose tissue for storage as fat. This is due to both insulin resistance, and to the limited storage capacity in muscles and the liver for glucose in the form of glycogen. I was writing colloquially and intentionally left out details like lipogenesis, which in retrospect probably wasn't a great idea.
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