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Re:Vitamin D Is a Hormone by tiffanyh on Monday March 18, 2024 @03:44PM (#39749056)
> I struggle to believe that a physician told her to take 5000 IU

Believe it.

When one of the most trusted vitamin companys (Nature’s Made) sells a 5000 IU single pill dosage that can be found at any drug or grocery store in the US - it nots surprising that people buy and believe 5000 is ok.

https://www.naturemade.com/products/nature-made-extra-streng...

If 4000 IU is the max dosage anyone should take, it shouldn’t be allowed for a compnay to sell a 5000 unit dosage.

Re:Vitamin D Is a Hormone by snakeyjake on Monday March 18, 2024 @04:22PM (#39749514)
I am 6'4" (193 cm) and 240 lbs (108 kg). A big boy. I require supplementation at 5000IU to maintain ~48 ng/mL, which is just about normal.

It is impossible, at my latitude, to obtain adequate exposure to sunlight. I tried that.

My doctor said "hmmmm your vitamin d is 9... maybe that explains the all-appendage tendonitis and muscle soreness" and recommended supplementation. I really like being able to spend 10¢ per day on D3 and K2 from Amazon instead of paying for 200,000 IU injections every month or two.

Re:Vitamin D Is a Hormone by Izkata on Monday March 18, 2024 @04:07PM (#39749322)
Re:Vitamin D Is a Hormone by HeadsUpHigh on Monday March 18, 2024 @05:03PM (#39749988)
The audacity to believe you know everything about this subject.

Super-high dosages are used in loading protocols before switching to a smaller maintenance dosage.

Re:Vitamin D Is a Hormone by wholinator2 on Monday March 18, 2024 @07:11PM (#39751171)
It didn't sound like arrogance to me. The "if" at the start of the sentence indicates they are not asserting their conclusion as the only truth. That said, if toxicity is a large concern, it's strange that companies sell such high dosages at least without some kind of warning. I bet a sufficient warning would prevent at least some cases of toxicity
Re:Vitamin D Is a Hormone by ghaff on Monday March 18, 2024 @10:32PM (#39752386)
A lot of OTC medications have potential issues and interactions. That said, my primary care recommended I take vitamin D based on blood work and no one has batted an eye at my taking 5K IU. So the idea that's some widely-accepted radically dangerous dose is simply untrue. (Doesn't mean it's a wrong idea but it's not one that doctors generally accept.)