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Re:Apple cider vinegar for weight management by vfvthunter on Sunday March 17, 2024 @05:52PM (#39738375)
The effect here seems to have little to do with gut microbiota: acetic acid itself induces the liver to stop making fats (lipogenesis) and start liberating fats into the blood (lipolysis). AcOH also by itself seems to decrease insulin resistance/increase insulin sensitivity, as well as downregulate gluconeogenesis. Several of the other studies in the bibliography confirmed this, and a couple even did tissue biopsies pre during and post to assess for changes in genetic expression of things like AMPK.

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