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Re:Prostate cancer includes two different evotypes by stergios on Wednesday March 13, 2024 @06:26PM (#39698352)
Gleason scores already designate 5 different types/categories of PaC, and this score strongly influences what type of barbaric treatment one will receive.

I hope their findings help discovery of humane immunotherapy’s.

Re:Prostate cancer includes two different evotypes by sroussey on Wednesday March 13, 2024 @06:29PM (#39698369)
My father was diagnosed with a Gleason score of 10 this year.

When it’s this bad, ironically some barbaric options are off the table.

Re:Prostate cancer includes two different evotypes by kmbfjr on Wednesday March 13, 2024 @06:55PM (#39698577)
I was just diagnosed with 7/7.5 Gleason score prostate cancer (adenocarcinoma).

The barbarians are cutting it out in 4 weeks.

A life of pissing my pants beats dying before retirement.

Re:Prostate cancer includes two different evotypes by stergios on Wednesday March 13, 2024 @07:20PM (#39698746)
I understand and agree. I was Gleason 7: 4+3 intermediate aggressive. Caught it very early, no spread, so RALP was performed 5 months ago. Now I’m deep in the throws of pelvic floor PT hoping to gain some semblance of control again.

Hopefully your surgeon has performed (unlike mine) more than 1000 RALPs - the incontinence outcomes improve greatly when their experience is that high.

Best of luck to you. DM me at gmail if you need/want to talk about your upcoming RALP.

Re:Prostate cancer includes two different evotypes by kmbfjr on Wednesday March 13, 2024 @07:43PM (#39698949)
I will do that. I am in a similar diagnosis.

I know someone who had the surgery 13 years ago and it went very well. But 5 months on for you, gives me the uneasies.

Re:Prostate cancer includes two different evotypes by wil421 on Thursday March 14, 2024 @05:52AM (#39701971)
My dad had it 14 years ago. It’s been in remission and to my knowledge there’s no accidents and I don’t think he had many issues from the start.
Re:Prostate cancer includes two different evotypes by fortran77 on Wednesday March 13, 2024 @09:50PM (#39699827)
There's a very good chance, 90% or higher, if you're under 70, not obese, and in general good health, that you will have no issues with impotence or incontinence after reovery from surgery.

This is really the best option for healthy fit people under 70.

Re:Prostate cancer includes two different evotypes by stergios on Wednesday March 13, 2024 @11:12PM (#39700245)
90% or higher? No way, there’s not a credible large scale survey that makes that claim. Closer to 15-25% suffer from incontinence permanently. And 30-50% will have ED. And 100% of outcomes will loose inches.

50% of RALP patients will have biochemical reoccurrence within 8 years. It takes 15 years of low PSA (<.1ng/ml) to state you are cured.

The goal is to die with PaC, not because of it.

All of these stats are available at PCRI.

Re:Prostate cancer includes two different evotypes by fortran77 on Thursday March 14, 2024 @09:27AM (#39703707)
> The goal is to die with PaC, not because of it.

The reason many people die "with" it is because 67% of Americans are obese or overweight, and it usually dosn't show up 'til a person is 70. Of course these people die of something else first.

If a person isn't fat, and has no other health problems, getting it removed if it hasn't spread beyond the prostate is the best choice.

Re:Prostate cancer includes two different evotypes by fortran77 on Thursday March 14, 2024 @12:12PM (#39705779)
See: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917389/

> Several studies report a progressive return of continence up to one year after RP, with a continence rate ranging from 68 to 97% at 12 months [13,14,15,16,17], while a progressive further improvement could be registered up to 2 years [18].

Note that I qualified it with under 70, good health otherwise, and non-obese or overweight. If you're in that category, you are extremely likely not to have continence problems after a year.