It's a long way from the cell culture to the human being when it comes to pharmaceutical effects. That is one of the main reasons it costs so much to develop new drugs--most compounds that produce promising effects in vitro are indistinguishable from placebo during human trials (if they even get that far).

The pharmaceutical industry actually tested BPA as an estrogen replacement decades ago, and did not adopt it because BPA did not produce measurable results. Today most of the BPA warnings are based on extrapolations from cell cultures. But based on the history of drug development such extrapolations are rarely valid. This is why U.S. regulatory agencies have not banned BPA; there just hasn't any solid evidence yet that BPA harms humans at the incidental levels of exposure most people experience.