Pharmaceuticals are a shockingly small part of the spend in healthcare in the US. Like ~10%.

Isn't that exactly what Mark Cuban is doing with Cost Plus Drugs Company?

I am sure there is room to improve things on the corporate side but I also feel that we need major structural changes on the government side. Both parties receive significant funding from insurance companies and both parties are so pro-corporate that it’s hard to find any viable candidates who will oppose expansion of bureaucracy as long as doing so ensures more profits. The real problems are systemic.

Cost Plus Drugs overwhelmingly just deals with generic drugs, but generic drugs are just a small fraction of total drug costs.