I assume the seal in screw caps is plastic which leaves micro plastics and/or PFAS behind in your drink.

The deduction is faulty.

PFAS are a specific family of chemicals unsuitable for this application.

No significant amount of microplastics is likely to develop from the mild abrasion of opening and closing a wine bottle a handful of times. And if your risk tolerance is so low that you are worried about that largely theoretical concern, you probably should not be drinking wine at all (because we have quite concrete evidence that alcohol is unhealthy -- unlike microplastics).

I would be (much) more worried about chunks of plastic getting in my wine from those fake cork products than from screw tops.

> No significant amount of microplastics is likely to develop from the mild abrasion of opening and closing a wine bottle a handful of times.

I think research has shown that simply storing acidic foods in contact with plastic causes micro plastics to release: https://pubmed.ncbi.nlm.nih.gov/37343248/

Once opened, they do not reseal as well as real cork.

This isn't a huge deal, because a separate tool made specifically for resealing wine bottles is better than either. But if you don't drink a whole bottle of wine at once, and you don't have such a tool, cork reseals better.