Fair, but I think there's a middle ground here, obviously an entire screen of buttons on top of a video occludes the content that you want to watch. Even if our visual cortex can handle it, I don't think its desirable if it can be avoided.

Of course, admittedly if all you have is a play button and a mute button (or some other very simple player) it probably doesn't matter much.

I think Twitch's UI is a good example of where the clutter goes too far. It's loaded with tons of distracting bits and bobs. Makes sense for their business model (most of these relate to how you can spend money on the platform), but from a user perspective it's unpleasant.