I'm not sure the protestors will be a net negative, lots of people protested trump in 2016 and them getting thrown out only encouraged his base. If you watch the videos of the Biden interruptions the crowd stays firmly on Biden's side.

Biden's issues at the moment are that economic sentiment is a lagging indicator of some variables that have only recently recovered to their normal values (inflation etc.). If these issues fix themselves we will have a better sense of whether Israel-Hamas War has meaningfully impacted him.