I've drank ayahuasca about 300 times (I work at a retreat center). 5-meo/bufo (especially at the "full release" dose) is probably the most profound experience I've had. To go "all the way", you really have to drop every attachment and accept that you are indeed dying in that moment (the freakouts happen when people are unable to and fight it). When you come back it's like being reborn. It is good for releasing a lot of stuff, but without many sessions things tend to come back pretty quick (it's good to be aware of those first things that come back- it's primo stuff to work on in therapy or ayahuasca/longer-lived psychs to really dig in to).

When looking for drug experiences, Erowid is probably the best resource I've ever found: https://www.erowid.org/experiences/subs/exp_5MeODMT.shtml