I'm on openSUSE TW, and I considered systemd-oom, but the setup/configuration procedure for it is pretty elaborate. So I opted for earlyoom, which worked just a fine and required no manual configuration whatsoever.

In my opinion, if your distro already integrates systemd-oom, like Fedora, it's easier to just use that. Otherwise earlyoom is the next best choice.

Also it's recommended to enable zram. It's much faster than a swap partition or file. The combination of earlyoom and zram made my system much more responsive when it's running short of memory.