Probably with a modifier key though so I don't move out of a game just to read a wiki page though.
However, I also find it easier to recall where I was looking by moving my head between static content instead of having it change.
FWIW I use a 32" screen positioned so that I barely need to move my head to see it all, and try to have all things I'm looking at visible at the same time.
I use virtual desktops as more to separate unrelated areas of work (like different projects). It's like having a completely different desk with different books open on it. Having more screen space is just like having a bigger desk. It's like having multiple books open on your desk at once as opposed to picking up one at a time to look at it.
One big monitor would be ideal (it could be split into an odd number of frames, for example), but in practice multiple monitors is a good compromise between flexibility and price.