I can relate to that feeling. I usually don't start enabling Adblock until a site I frequent does something particularly noxious.

One example was my local newspaper, which put this flash overlay of a local bigmouth car deal floating in the middle of the screen -- in a area that you typically click on.

I click it by mistake and end up with a high-volume "it's huuuge" booming across my office. Screw that... adblock=on.