WFH is existentially painful for those that have coupled their identity too strongly to their jobs. They're confronted daily with the fact that their coworkers just aren't that into them (e.g. the job, and by extension, them) as they'd like. The likelihood this has happened goes up significantly as you move up the ladder, because the volcano gods demand sacrifice for that.

There's also a segment of the population that somewhat overlaps with the previous paragraph that uses work as their primary social outlet.