Yes, I was just thinking of an acquaintance's similar cancer situation in the UK. The NHS denial of the more effective but more expensive treatment was intractable, and so they paid for the treatment out of pocket through a fundraiser and saved her life. Their fundraiser was successful enough that they were able to give some money to other UK residents in the same situation. In the US I think they could have at least switched jobs to get it covered if they couldn't hack the appeals process.