I'm no expert but I actually think we are pretty good at genetically modifying organisms and that manifests itself in crops for instance with enough research to support the benefits.

Plants are one thing we do it well enough on. As far as I'm aware we have yet to do it (at scale) on livestock, or even pets.

There is: https://en.wiktionary.org/wiki/Enviropig or https://en.wikipedia.org/wiki/AquAdvantage_salmon

or things to the likes of https://www.avma.org/news/genetically-modified-cattle-may-be...

Looks like the fish is the only one that's gone to market. Pretty clearly still early days. I have no doubt that with enough time we'll get there, but to say this is proof that we're technically good to go ahead and produce gmo humans seems a bit rushed -- to reiterate, the point being that the ethical issues here are much more clear than a trolley problem or stack of hypotheses.

I think much of this is, because Monsanto aside, no one has had a nice big genetic accident or intentional 'oh no' yet. Yea, we've had issues but not at the people are starving.

If we start thinking of plant based biological weapons, just imagine modifying an existing grass to produce tons of pollen and to cross pollinate wheat but not produce seed in the wheat.