Thats a great connection you've made between seemingly disconnected & distant disciplines. If we figure out the actual biological and chemical processes involved in a human body while it is indulging in synthesizing an 'original sin', that would be a big win in terms expanding our species' knowledge-base.

I'm sure there's research out there that explains at least fews bits of it through experiments where they monitor bodily processes when a person is lying. There are some common methods like the lie-detector and GSR methods, but apart from those external monitoring methods, probably also some molecular/cellular-level observations have been made.