If you're using Chrome on mobile, and the differences between the desktop versions are negligible, why would you not just stick to Chrome on desktop as well?
I think this is actually a good example of where Firefox could really make a difference on desktop. Introduce a very powerful extension framework, allowing things like what Chrome is removing in manifest v3. Killer extensions will be built and people will switch for that. For the users who would inevitably install malware extensions, there will always be Chrome. Firefox doesn't need 100% market share, just one big enough that it can't be ignored.
Can you point out what you feel is the single most noticeable difference? I use Firefox as my daily driver but I also use Chrome, and I never noticed any difference.
I find Firefox to be noticeably slower than the various Blink-based browsers and Safari (when available) when running on the same systems. I'm referring to the overall responsiveness of the UI and the application itself, as well as the rendering of sites, and the subsequent interaction with them. I find this to be the case for a fresh installation with no extensions, all the way through to an installation with common ad blocker extensions installed. Firefox is just plain slower, from what I can tell.
Firefox's extension signing nonsense is another pain point. As part of my work, there's a fully-trusted custom extension developed in-house that I need to install. It's trivial to install in the various Blink-based browsers. On the stable releases of Firefox, though, I have to jump through numerous hoop to get it installed and usable, and this has to be done each time the browser restarts, which is often in my case.
Chrome on the other side has good integration into Googles ecosystem, has better support from Webapps (yes, this sometimes is a relevant topic), is depending on the platform significant faster, and seems to have some better side-features here and there. So its whole identity is to be THE Google-Browser, well polished for the modern World Wide Web.
Similar stuff is with Opera, Vivaldi, they all have their own special identity which they support with accompanying features. Like Vivaldi being an app-suite which offers more than just web browsing, or Opera with their Gaming-Browser catering to give gamers a good selling point. Not sure that Brave is doing today, but they were once strongly focused on AdBlock and earning Money?
Firefox on the other side has nothing of this. It once was the everything-browser, which could be anything through extensions. A mail-client, ftp-client, web-archiver, note-app, office suite, and much much more, all depending on the Users preferences. But that is lost, and now it can't even restore lost basic features. At this point it's just a window to render Web-stuff, with a better Adblocker and customization than Chrome. And even this is not advertised well. I mean the last ads I saw from Mozilla were not even about anything specific, just random pictures...
I think the decline of Firefox market share has a lot more to do with forces outside of its control than the quality of the product.