Are the dividends that significant over using CUA shortcuts* that usually are available in most other places?

I've done some reading and I'm considering diving into Vim, but I'm not sure, at least without much experience the surface level feels achievable by 2 keystroke combos and the mental overhead of getting used to using vim style bindings in some places but not others feel like exactly the kind of friction the article is trying to avoid

* Like navigating using Home, End, PgUp/Dn, moving between lines by Ctrl+arrows, Ctrl+X'ing for yanking etc