At least today, my experience is that Pyright is faster, flags more issues, provides better error messages, and (alas for Mypy) has fewer bugs. I hope this will change over time as Mypy matures, but there you have it.

When using Pyright in large Django projects, it's helpful to add explicit type annotations in a number of places (like reverse relations in Models) but I've found this tends to improve the clarity of the resulting code anyway.