I personally like the flexibility of i3's keybinding config.[1] For each binding it lets you choose either:

- a keysym (the letter Z, wherever it happens to be in your current layout)

- or a keycode/scancode (the physical button under your pinky, no matter the current layout)

I use both methods for different bindings. For example I've bound the vim keys (hjkl) by scancode, and the layout keys ("S"tack, "F"ullscreen, "R"esize, etc) by symbol.

[1]: https://i3wm.org/docs/userguide.html#keybindings