I'm wondering this same thing - my current assessment is no and that a YAML config is superior to compile-time macros. If I used Shuttle, I'd probably be using cfg-if and type aliases anyway to stop it from infecting the majority of my code. The proposed benefit of having a compile-time validated config is not a tangible one in my opinion. I don't think the abstractions are that beneficial either.

This is kind of a harsh assessment, but maybe it's just not for me.