If we follow your "it's illegal because there's a probability" theory of law enforcement, then it should only be illegal to do drugs while poor, which is pretty much where the law stands today without the deceptive veneer of equality. Now, that should sound like an absurd legal take, because it is. The reasonable response is that it's poverty that's the problem, and it's not a problem we solve by throwing all the poor people in jail.
The Poverty Industrial Complex (i.e., law enforcement, gov agencies, non-profits) is quite content with a persistence of the status quo.
Do you have hard data on this? Because otherwise you are creating lots of victims with the war on drugs, who would otherwise just use drugs recreational without harming anyone.
It's a big consideration in what's OTC vs Rx, and what guardrails (inpatient only, regular blood draws, etc) are needed.
There was a good "magic quadrant"-style plot of this against addictive potential, but I can't seem to find it just yet. (This [2] is close.)
It doesn't consider externalities, so it's not great for the "do drugs and you'll end up unemployed, and if you're unemployed you'll end up homeless, and homeless people are a cost on the community" class of arguments.
[1] https://en.wikipedia.org/wiki/Therapeutic_index
[2] https://en.m.wikipedia.org/wiki/File:Rational_scale_to_assess_the_harm_of_drugs_%28mean_physical_harm_and_mean_dependence%29.svg
Hard drugs are really, really bad for you, and really bad for society. It really is the drug that is the problem - some substances simply cannot be used safely for recreation. If you choose to take them, you're rolling the dice on where you'll end up, and that makes it a crime with society as the victim.