My experience is that I was unable to debug Maestral (a Python program) crashing in native Cocoa bindings in LLDB, because the interpreter did not allow itself to be debugged. Mozilla says Firefox acts the same way at https://firefox-source-docs.mozilla.org/contributing/debuggi.... It's possible there's some workaround I'm not aware of, but I ended up disabling SIP just like every non-macOS computer I own.