I think the point being made is that this medical intervention, which has been approved to treat obesity via weight loss, is going to give people sarcopenia and ruin their bone mineral density. During the clinical trials, there was no analysis of body composition (via DXA or other means) which would have given patients more informed perspective about this issue.

It's a good shim considering the obesity rate in developed countries, but something superior would be a biological mechanism to inhibit the body's uptake of sugars. Instead of reducing appetite, which reduces intake of critical macros and minerals, you're then instead preventing the body from processing the worst offender in western diets. Eating healthy is challenging in the current macro (cost, access, time, etc).

Then perhaps the best treatment would be to combine a GLP-1 Agonist and sex-hormone replacement.