Re:The human Y chromosome has been completely sequenced
by panosfilianos on Friday August 25, 2023 @12:48AM
(#37258204)
I have spent the better part of the past year looking obsessively over genomics papers for cancer and I've grown very fond of the field.
Are there any positions at Google/ companies you wold suggest me to look into? I'm coming from algortrading/ ML research with ML MSc.
Re:The human Y chromosome has been completely sequenced
by asielen on Friday August 25, 2023 @01:38AM
(#37258479)
You could try Calico. They are an Alphabet company that specifically studies aging. There how a good amount of machine learning roles. However biotech typically pays less than finance or software.
Re:The human Y chromosome has been completely sequenced
by panosfilianos on Friday August 25, 2023 @02:05AM
(#37258610)
Thanks!
Re:The human Y chromosome has been completely sequenced
by krab on Friday August 25, 2023 @02:14AM
(#37258654)
But why Google? This is what big pharma are doing. Also you can outsource the data collection part. See for example UK Biobank. Their data are available to multiple companies after some period so it makes it more cost efficient.
Re:The human Y chromosome has been completely sequenced
by dekhn on Friday August 25, 2023 @11:45AM
(#37263023)
Why Google? Because this is a big data problem and Google mastered big data and ML on big data a long time ago. Most big pharma hasn't completely internalized the mindset required to do truly large-scale data analysis.
Re:The human Y chromosome has been completely sequenced
by 2dvisio on Friday August 25, 2023 @03:19AM
(#37259024)
Guys at Verily are working on Terra.bio with the Broad institute and others. Genomics England in the UK is also experiencing with multimodal and machine learning applied to whole genome sequences [1].
[1] https://www.genomicsengland.co.uk/blog/data-representations-...
The really interesting approaches these days, IMHO, combine genomics and microscopic imaging of organoids, and many folks are trying to set up a "lab in the loop", in which large-scale experiments run autonomously by sophisticated ML systems could accelerate discovery. It's a fractally complex and challenging problem.
Statistics has been key to understanding genetics from the beginning (see Mendel, Fisher) and so at a big pharma you will see everything from Bayesian bootstrappers using R to deep learners using pytorch.