I'm a bit concerned about at least one measurement:
Read 16-byte file 100000 iterations 2.1s for 100k reads 21219.3ns per read
This appears to be testing... the filesystem cache? It's certainly not seeking on a rotational disk, "SSD" isn't on the page, so... not sure where he's getting 21 microsecond reads from.
It's measuring the overhead of a set of open()/read()/close() syscalls - exactly the situation where you would want to use the cache to avoid physical disk latencies swamping the language variation.
http://www.mikeash.com/pyblog/performance-comparisons-of-com...